The product can be used with the eye open or closed. Shake before use; when using for the first time, push down on the nozzle 3 to 4 times. Hold the bottle firmly, place the thumb on the dispenser taking care not to cover the nebuliser with your finger. Hold the nebuliser about 10 cm from the eye, positioned to the side. If you use the product with your eyes open, keep looking forward so that the bottle is at the lateral edge of the visual field. Apply pressure to the dispenser to produce an effective mist. It is advisable to spray twice for each application. Repeat one or more times a day. Dispose of the device according to local laws.